5 Panel Drug Test Cups & Kits — CLIA-Waived & FDA-Cleared

What is a 5 panel drug test?

A 5 panel drug test screens a urine specimen for the five substances mandated under the U.S. Department of Health & Human Services (HHS) Mandatory Guidelines for Federal Workplace Drug Testing Programs — commonly known as the SAMHSA-5:

  • Amphetamines (AMP) — including methamphetamine and MDMA derivatives
  • Cocaine (COC) — via the benzoylecgonine metabolite
  • Marijuana (THC) — via the 11-nor-THC-COOH metabolite
  • Opiates (OPI) — codeine, morphine, heroin metabolites
  • Phencyclidine (PCP)

The 5 panel test is the federally-required configuration for all DOT-regulated testing programs under 49 CFR Part 40, and is the most cost-effective panel for general workplace, pre-employment, and reasonable-suspicion testing.

Who uses 5 panel drug tests?

  • DOT-regulated employers (FMCSA trucking, FAA aviation, FRA rail, FTA transit, PHMSA pipeline, USCG maritime) — required by 49 CFR Part 40
  • Non-DOT employers running budget-conscious workplace testing programs
  • Federal agencies and contractors subject to the Drug-Free Workplace Act
  • Probation and parole programs with standard panel requirements
  • Athletic and educational programs

Key features of ASC 5 panel cups

  • CLIA-waived — usable at the point of care by trained non-laboratory personnel
  • FDA 510(k) cleared — legally marketed in the United States
  • SAMHSA-aligned cutoffs — standard cutoff levels match federal guidelines
  • Results in 5 minutes — rapid turnaround for point-of-care decisions
  • Integrated temperature strip — specimen validity check within 4 minutes
  • 97-99% accuracy vs. laboratory GC-MS confirmation
  • 18-24 month shelf life at standard ambient temperature (no refrigeration required)

Shop 5 panel drug tests

American Screening Corp manufactures and distributes a full line of 5 panel drug test cups, dip cards, and saliva tests. Browse the catalog or request a free sample for evaluation.

5 panel drug test FAQ

Are 5 panel drug tests still required under DOT?

Yes. As of 2018, DOT testing includes oxycodone, oxymorphone, hydrocodone, and hydromorphone within the "opiates" category — sometimes called the "expanded opiate" 5 panel. The base panel structure remains 5 substances.

What's the difference between a 5 panel and 10 panel test?

A 10 panel adds five additional substances: benzodiazepines, barbiturates, methadone, methamphetamine (separately scored from amphetamines), and propoxyphene. Higher panels are used in non-DOT settings or expanded compliance programs. See our 12 panel drug test page for extended panel options.

Is bulk pricing available for 5 panel cups?

Yes — pricing tiers begin at 100 units with significant discounts at 500, 1,000, 5,000, and 10,000+ unit levels. Request a quote or call 318-798-3306. NET 30 terms are available for qualified business accounts.


Ready to order? Browse CLIA-waived cups, request a free sample, or call 318-798-3306 for bulk pricing.